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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
28.79
Human Site:
S674
Identified Species:
45.24
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S674
E
M
M
R
V
G
L
S
Q
D
A
Q
D
Q
M
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S674
E
M
M
R
V
G
L
S
Q
D
A
Q
D
Q
M
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
D417
K
S
E
Q
Y
D
L
D
S
L
C
A
G
V
E
Dog
Lupus familis
XP_534537
1097
121903
Q659
Q
M
R
K
I
L
Y
Q
K
E
S
N
Y
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S673
E
M
M
R
V
G
L
S
Q
D
A
Q
D
Q
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
S664
E
M
M
R
V
G
L
S
Q
D
A
Q
D
Q
M
Chicken
Gallus gallus
XP_419666
1136
127431
S680
E
M
M
R
V
G
L
S
P
E
A
R
D
Q
M
Frog
Xenopus laevis
NP_001087838
1118
125984
S660
E
M
M
R
V
R
L
S
Q
E
A
Q
D
Q
M
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
G652
F
E
K
I
K
T
L
G
I
G
A
F
G
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
P688
E
M
H
K
V
G
L
P
D
Q
T
Q
I
E
M
Honey Bee
Apis mellifera
XP_395146
1137
124999
S710
E
M
A
K
I
G
L
S
A
E
A
Q
C
Q
M
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
V84
L
K
R
T
R
L
T
V
N
D
F
E
S
L
K
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
T750
E
M
Q
R
V
D
L
T
S
G
D
R
D
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
G364
V
I
G
K
G
A
F
G
E
V
R
L
V
Q
K
Red Bread Mold
Neurospora crassa
P38679
598
67999
R206
G
Q
Y
L
R
F
L
R
T
K
D
K
P
E
N
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
6.6
N.A.
100
N.A.
N.A.
100
80
86.6
13.3
N.A.
46.6
60
6.6
53.3
P-Site Similarity:
100
100
20
46.6
N.A.
100
N.A.
N.A.
100
93.3
93.3
26.6
N.A.
60
80
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
7
0
54
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% C
% Asp:
0
0
0
0
0
14
0
7
7
34
14
0
47
0
0
% D
% Glu:
60
7
7
0
0
0
0
0
7
27
0
7
0
20
7
% E
% Phe:
7
0
0
0
0
7
7
0
0
0
7
7
0
0
0
% F
% Gly:
7
0
7
0
7
47
0
14
0
14
0
0
14
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
14
0
0
0
7
0
0
0
7
0
0
% I
% Lys:
7
7
7
27
7
0
0
0
7
7
0
7
0
0
14
% K
% Leu:
7
0
0
7
0
14
80
0
0
7
0
7
0
7
0
% L
% Met:
0
67
40
0
0
0
0
0
0
0
0
0
0
0
60
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
7
0
7
7
% N
% Pro:
0
0
0
0
0
0
0
7
7
0
0
0
7
0
0
% P
% Gln:
7
7
7
7
0
0
0
7
34
7
0
47
0
60
0
% Q
% Arg:
0
0
14
47
14
7
0
7
0
0
7
14
0
0
7
% R
% Ser:
0
7
0
0
0
0
0
47
14
0
7
0
7
0
0
% S
% Thr:
0
0
0
7
0
7
7
7
7
0
7
0
0
0
0
% T
% Val:
7
0
0
0
54
0
0
7
0
7
0
0
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
7
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _